Normal Pressure Hydrocephalus (NPH): A Highly Treatable Brain Disorder

Ever since Billy Joel revealed on Instagram that he was suffering from normal pressure hydrocephalus (NPH), his condition has become big news, along with the surgical treatment that has eased his symptoms.听
With early diagnosis, a skilled neurosurgeon can provide the treatment capable of reversing its harmful effects; a neurosurgeon like Dr. Jared Knopman.听听
Dr. Knopman wears multiple hats within 91麻豆精品. 贬别鈥檚 the Director of Cerebrovascular Surgery and Interventional Neuroradiology鈥a specialty involving the use of high-tech imaging to guide advanced surgical techniques for vascular disorders of the brain and spinal cord. 贬别鈥檚 also an Associate Professor of Neurological Surgery and Fellowship Director for Endovascular Neurosurgery.听
Keep reading for answers to your FAQs about a condition that affects from 3 to 5 percent of older adults but can be difficult to diagnose.听听
What is NPH?听
NPH occurs when 迟丑别谤别鈥檚 a buildup of fluid in cavities, called ventricles, that lie deep within the brain. 鈥淣辞谤尘补濒濒测,鈥 Dr. Knopman says, 鈥渃erebrospinal fluid bathes the brain and spinal cord, protecting them from injury and filtering the waste produced by brain metabolism. But when a patient has hydrocephalus, the brain鈥檚 plumbing gets clogged. As a result, 迟丑别谤别鈥檚 an imbalance between how much fluid is produced and how much gets absorbed into the bloodstream.鈥听
The build-up of too much fluid can damage brain tissues and cause what he calls a classic triad of symptoms.听
What are the characteristic symptoms of NPH?听
While NPH can occur in any age group, its symptoms in older adults typically follow a recognizable pattern, including:听
- A loss of bladder control听听
- Gait disturbance听
- Cognitive decline听
鈥淧atients may have one, two or all three of these,鈥 he says, 鈥渁nd they can easily be mistaken for other age-related issues.鈥 贬别谤别鈥檚 why.听
Urinary incontinence is common among older people. 滨迟鈥檚 often associated with an enlarged prostate, prostate cancer or weakening of the pelvic floor muscles鈥攁ll conditions that become more prevalent as people age.听听
The gait disturbance (abnormal walking) 迟丑补迟鈥檚 often seen in older people with NPH is characterized by a shuffling quality, and the patient鈥檚 feet tend to be spread wide apart as they walk, appearing to have a walk that looks 鈥渕agnetic鈥 to the floor. But such gait problems can also be caused by back or knee problems, which need to be ruled out before an NPH diagnosis can be confirmed, Dr. Knopman says.听
And third, cognitive decline, or dementia, is often associated with neurodegenerative diseases like Parkinson鈥檚 and Alzheimer鈥檚. These, too, are fairly common among older adults.听
However, when all three of these classic symptoms are seen together, NPH is usually the culprit. An MRI will show the presence of excess fluid in the ventricles, thus suggesting a diagnosis of NPH.听听
Do these symptoms appear suddenly or gradually?听
The symptoms of NPH tend to be progressive and slow-growing, he explains. 鈥It can take several months, a year or even longer for them to become noticeable enough for a family member to bring their loved one in for diagnosis and treatment.鈥听
Is there a difference between normal pressure and 鈥渢raditional鈥 hydrocephalus?听
The short answer is yes. While the symptoms of NPH tend to come on gradually, those associated with traditional hydrocephalus may appear quite suddenly.听听
The pressure inside your skull 迟丑补迟鈥檚 associated with NPH is mostly within the normal range, most likely because your brain has time to adjust to the excess fluid. By contrast, the rapid onset of symptoms seen in traditional hydrocephalus creates a higher level of intracranial pressure.听
Still, both types of hydrocephalus are treated in the same way, Dr. Knopman says.听
What is the gold standard for the treatment of hydrocephalus?听
鈥淲e insert a ventriculoperitoneal (VP) shunt鈥攁 small tube鈥攊nto the brain, which reroutes the excess fluid into the abdomen, where the body can absorb it,鈥 he says. 鈥淭he procedure only takes about an hour, and patients usually stay in the hospital for a day or two.听听
鈥淭he shunt includes a valve that can be adjusted over time to meet individual needs,鈥 he adds.听听
How long does it take to recover from the procedure? From NPH itself?听
Recovery is gradual, with most patients experiencing improvement over several months. Sometimes, he says, 鈥減atients can even get better within a few weeks after shunting.鈥听
Prospects for a return to normal are excellent when NPH is diagnosed early and treated appropriately. From 80 to 90 percent of patients show significant improvement, if not total resolution, in short order.听
Are there ever complications in the aftermath of shunting?听
Complications are relatively rare, says Dr. Knopman, occurring in roughly 10 percent of patients. The main risks have to do with the shunt鈥檚 malfunctioning, getting clogged with protein or getting infected. In these cases, it will need to be removed and replaced.听
A hopeful picture听
Although brain disorders are often serious, NPH stands out for its treatability when caught early.听
鈥淲ith timely and proper treatment, most patients go on to live full, active lives,鈥 he says.听
Billy Joel鈥檚 openness in sharing his condition has raised awareness around an often-overlooked disorder that affects thousands of older adults every year.听听
At this rate, Dr. Knopman predicts, 迟丑别谤别鈥檚 every reason to believe 飞别鈥檒濒 see the piano man back on stage鈥濃攕ooner rather than later!听
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